What are cell and tissue growth factors?
Bovine colostrum contains very important growth factors that help with the repair of damaged cells and tissues. Growth factors are proteins which are responsible for cell growth and repair. Below are listed the important growth factors present naturally in bovine colostrum an explanation of their role within the body.
List of cell and tissue growth factors naturally present in colostrum:
- Transforming growth factor (TgF - A & B)
- Insulin-like growth factor (IgF-1 & 2)
- Fybro blast growth factor (FgF)
- Epithelial growth factor (EgF)
- Platelet-derived growth factor (PDgF)
- Trypsin and Protease inhibitors
- Growth Hormone (GH)
What is their function?
TgF - Transforming growth factor
TGF stimulates the renewal of cells in connective tissue and assists in the formation of bone and cartilage. TGF can help repair damaged tissue and supports growth of the lining of the gut.
IgF-1 & 2 - Insulin-like growth factor 1 & 2
IgF I & II are the most abundant growth factors in bovine colostrum. They play an important role in the way the body uses sugars, fats and proteins.
IgF-1 helps to increase lean muscle mass, repairs DNA and RNA, regulates blood-sugar and cholesterol levels. Almost every cell in the human body is affected by IGF-1, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs. In addition to the insulin-like effects, IGF-1 can also regulate cell growth and development, especially in nerve cells, as well as cellular DNA synthesis.
IgF-2 is responsible for how the body uses fat and proteins.
FgF - Fibroblast growth factors
FgF growth factor enhances wound healing, tissue growth and repair. It especially important for blood vessel growth.
EgF - Epidermal growth factor
EgF growth factor in bovine colostrum plays an important role in the regulation of cell growth, proliferation and differentiation. It helps to protect and maintain the skin.
PDgF - Platelet-derived growth factor
PDgF growth factors are important for stimulation of connective tissue; it plays a role in wound healing and helps with cell division. It also assists in neuron survival and regeneration.
Trypsin and Protease inhibitors
Trypsin and protease inhibitors help prevent the destruction of immune and growth factors by the enzymes present in the gastrointestinal tract. They also help prevent ulcer causing bacteria and are very important in the healing of gastric ulcers.
Growth Hormone (GH)
Growth hormone (GH) is a hormone that stimulates growth and cell reproduction in humans and other animals. It is the most abundant hormone in the body and is involved in the regeneration of major organs such as the heart, lungs and liver. It also helps to increase protein synthesis which is crucial for skin and bode renewal.