Short bowel syndrome
About short bowel syndrome
Short bowel syndrome is a malabsorption disorder caused by the surgical removal of the small intestine, or, rarely, by the complete dysfunction of a large segment of bowel. Most cases are acquired, although some children are born with a congenital short bowel. It usually does not develop unless a person has lost more than two thirds of their small intestine.
Signs and symptoms
The symptoms of short bowel syndrome can include:
- Abdominal pain
- Diarrhea
- Fluid retention
- Weightloss and malnutrition
- Fatigue
How holvita™ colostrum can help people with short bowel syndrome
Some patients have an insufficient length of bowel to digest and absorb food adequately, usually as a result of massive intestinal resection for vascular insufficiency or after repeated operations for inflammatory bowel disease. Current therapeutic options are unpleasant and associated with a high risk of morbidity or mortality, eg, long-term parenteral (intravenous) feeding and small-bowel transplantation. Strategies to optimize the function of the residual bowel and ultimately wean patients off total parenteral nutrition would therefore be of great benefit. There is evidence that growth factors could be instrumental in achieving this goal; eg, systemic administration of individual growth factors such as EGF have been shown to stimulate bowel growth in rats receiving total parenteral nutrition (77). In addition, oral administration of EGF helped restore glucose transport and phlorizin binding in rabbit intestines after jejunal resection (78), and colostrum supplementation of piglet feeding regimens resulted in a significant increase in intestinal proliferation (79). Colostrum supplementation may be of particular value in young children who have undergone intestinal resection because gut adaptation is more likely during early childhood than it is in adulthood.
Our holvita™ colostrum can be very beneficial to people suffering with short bowel syndrome because it helps to heal the intestinal lining and contains nutrients which are easily absorbed. Colostrum also regenerates all body's cells it helps to raise energy levels by improving the metabolism and nutrients uptake.
References
77. Playford RJ, Boulton R, Ghatei MA, Bloom SR, Wright NA, Goodlad RA. Comparison of the effects of TGF and EGF on gastrointestinal proliferation and hormone release. Digestion 1996;57:362–7.[Medline]
78. O'Loughlin W, Winter M, Shun A, et al. Structural and functional adaptation following jejunal resection in rabbits: effect of epidermal growth factor. Gastroenterology 1994;107:87–93.[Abstract]
79. Kelly D, King TP, McFadyen M, Coutts AGP. Effect of preclosure colostrum intake on the development of the intestinal epithelium of artificially reared piglets. Biol Neonate 1993;64:235–44.[Medline]
Kim, JW, Jeon, WK, Yun, JW, Park, DI, Cho, YK, Sung, IK, Sohn, CI, Kim, BI, Yeom, JS, Park, HS, Kim, EJ, Shin, MS. (2005) Protective effects of bovine colostrum on non-steroidal anti-inflammatory drug induced intestinal damage in rats. Asia Pacific Journal of Clinical Nutrition 14(1):103-7
Playford RJ, Macdonald CE, Johnson WS; American Journal of Clinical Nutrition, Vol. 72, No. 1, 5-14, July 2000. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders.
Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T., Gut. 1999 May;44(5):653-8. Related Articles, Links, Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. University Division of Gastroenterology, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK. Pluske, JR, Morel, PCH. Increasing weaner pig productivity in New Zealand pig herds. Factors associated with grower herd performance in three New Zealand pig farms (1999). Piglets fed a liquid supplement with colostrum powder had a marked increase in villi height in the lumen of the small intestine, indicating greater digestion and absorption of nutrients. There were also an increased number of immune cells in the villi, indicating enhanced immune competency.
Purup, S, Vestergaard, M, Pedersen, O, Sejrsen, K. (2007) Biological activity of bovine milk on proliferation of human intestinal cells. Journal of Dairy Research 74(1):58-65. Bovine milk contains a number of biologically active components that affect growth development of human intestinal tissue. The degree of activity depended on the stage of lactation.
Bioactive components for the treatment of gastroinstwestinal disorders Author(s): Ghosh S, Playford RJ. Clinical Science (London, England : 1979). 2003 June; 104(6): 547-56. Review.