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Colostrum references

In this section you can read and find all references and research that has been done with colostrum within the scientific field.

  • Ulcova-Gallova, Fialova, Krauz, 1994, Clinical Study: Cas Lek. Cesk. May 2, Vol. 133(9) pp. 275-6. Reported that: A. Immunofactors present in bovine colostrum are IgG, IgM, IgA, sIgA, SCIgA, C3, C4, Orosormucoid, Prealbumin, Alpha 1- anitrypsin, Alpha-1 fetoprotein, Alpha-2 Macroglobulin, Alpha2- AP Glycoprotein, and IgE. B. An important immunological liquid with proven bacteriostatic and viral inhibitory activity preventing penetration of pathogenic microorganisms and absorption of potential allergens into the digestive tract.
  • Deitch, E. A., 1990, Arc Surgery: Vol 125: p403-4; 'The role of intestinal barrier failure and bacterial translocation in the development of systemic infection and multiple organ failure.'
  • Patureau- Mirand, Posone, Levieux, Attaix, et. al, 1990, Biol. Neonate Vol. 57(1): 30-6 Reported that Colostrum stimulated intestinal protein synthesis. Association": French doctors showed that a combination of IgG and Lactoferrin in colostrum was bacteriostatic for E. coli.
  • Author(s): Huppertz HI, Rutkowski S, Busch DH, Eisebit R, Lissner R, Karch H. Journal of Pediatric Gastroenterology and Nutrition. 1999 October; 29(4): 452-6. Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, shiga toxin-producing E. Coli, and E. coli expressing intimin and hemolysin.
  • (Beth M. Ley, P.h.D; Immune system control: Colostrum and lactoferrin. 1969 (2000); p69-70.)
  • (Beth M. Ley, P.h.D; Immune system control: Colostrum and lactoferrin. 1969 (2000); p69-70.) “Research has show that colostrum can provide protection against a wide range of pathogens and demonstrated when taken orally to be effective against disease causing bacterial in the intestinal tract. (McLead)”
  • McClead, R. et. al., 1979, Pediatrics Research, Vol, 13 No. 4, 2 of 2, 464. Human clinical study completed using immungolubulins and antibodies from cow colostrum providing its effectiveness against disease-causing bacteria. Presented in 1979 by and Dr. R. McClead and associates at the 89th annual meeting of the American Pediatric Society. It was demonstrated that immune factors in cow colostrum, when taken orally, are effective against disease-causing organisms in the intestinal tract. Their report concludes, “Ignestion of bovine Colostrum immunoglobulins – may be a new method of providing passive immunoprotection against a host of gut-associated antigens.”
  • Hamilton, Whitney and Sizer, 1985, Nutrition: Concepts and Controversies, West Pub. (Nutritional textbook): (Bovine) Colostrum contains a bifidus factor that favors the growth of friendly intestinal bacteria. Also contains huge counts of active Lactobacillus Bifidus. Also reported that Lactoferrin in Colostrum keeps invading bacteria from getting iron needed to reproduce.
  • Shin K, Yamauchi K, Teraguchi S, et al. (1998) Antibacterial activity of bovine lactoferrin and its peptides against enterohaemorrhagic E. coli O157:H7. Letters in Applied Microbiology. 26:407-411.
  • Huppertz HI, Rutkowski S, Busch DH, Eisebit R, Lissner R, Karch H., J Pediatr Gastroenterol Nutr. 1999 Oct;29(4):452-6. Related Articles, Links, Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, shiga toxin-producing E. Coli, and E. coli expressing intimin and hemolysin. Children's Hospital, The University of Wurzburg, Germany
  • Korhonen, H, et al. Milk immunoglobulins and complement factors. British Journal of Nutrition 84(Suppl.1):S75-S80 (2000). Bovine colostrum contains three main classes of immunoglobulin IgG (IgG1 75% and IgG2), IgM and IgA, plus hemolytic and bactericidal complement. Complement is a complex group of proteins which act in concert with antibodies to inactivate and/or kill pathogens.
  • Spik,G. et. al., Immunology, Vol. 35 No 4, 663-671. (Bovine) Colostrum contains a special iron binding protein called Lactoferrin which was demonstrated at the Clinical Research \center, Harrow, England to be highly antibacterial.
  • Klapper, D.G.. et. al., 1983, Endocrinology; 112 (6) 2215-7. pp 13-18: Oligo and polysaccharides in colostrum bind many types of bacteria and prevent them from attaching to or entering the body though the mucal membranes.
  • Moldoveanu, Zina, et. al., 1983, Annals of NY Academy of Sciences, 409, pp. 848-850: "Antibacterial Properties of Milk: IgA-Peroxidase Lactoferrin Interactions": Combination of peroxidase, lactoferrin and IgA in (bovine) Colostrum produces strong combined antibacterial effect. Peroxidase enzymes oxidize bacteria .by ' generating the release of Hydrogen peroxide which burns up (hydrolyses) harmful bacteria.
  • Appelmelk, Ben J.; et al. Infection and Immunity, Vol. 62, No. 6, June 1994, 2628-2632. Lactoferrin Is a Lipid ABinding Protein. This research shows that lactoferrin acts as a preventative against ingested bacteria.