
Colostrum and Rotaviruses
About Rotaviruses
Rotavirus are one of the leading causes of diarrhoea among infants and young children throughout the world as well as the elderly and immunocompromised people. There are seven species of rotavirus classified as A, B, C, D ,E, F and G. Rotavirus A is the most common strain and causes over 90% of infections in humans. The virus is transmitted by the oral route when faecal matter is ingested. It infects the cells within the small intestine and produces toxins which cause severe diarrhoea.
Viruses and our health
Viral infections in humans and animals mostly result in an immune response and disease, but most of viruses are eliminated by their immune system.
Examples of diseases caused by viruses are colds and flu, chicken pox, hepatitis, measles, herpes, viral pneumonia, shingles, Epstein Barr virus, respiratory syncytial virus, AIDS and numerous others. They are also viruses causing diarrhoea and other life-threatening diseases.
Antibiotics have no effect on viruses, but some antiviral drugs have been developed to treat life-threatening infections.
How holvita™ colostrum help against rotaviruses
Brüssow, H., et al. Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis. Journal of Clinical Microbiology 25(6):982-986 (1987). Protection against rotavirus, a dangerous pathogen which can cause serious, even fatal diarrhoea in infants, can be passed orally through milk or colostrum safely and effectively. Colostrum contains anti-viral factors which boost immunity and help to fight viral infections. Lactoferrin, immunoglobulins help to fight pathogens and growth factors help to heal and regenerate the intestinal walls and flora which results in reduced dirrhohea. (Mitra)
Our holvita™ colostrum contains a high concentration off immunogolublins and other components helping to fight rotavirus infection.
References:
Beth M. Ley P.h.D Immune System Control: Colostrum and Lactoferrin 1969 (2000) p115.
Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T. Kansenshogaku Zasshi. 1990 Mar;64(3):274-9. Related Articles, Links,[Immunoglobulin components and anti-viral activities in bovine colostrum][Article in Japanese],Department of Enteroviruses, National Institute of Health, Japan
Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T. (1990) Immunoglobulin components and anti-viral activities in bovine colostrum. Kansenshogaku Zasshi. 1990 Mar;64:274-279.
van Hooijdonk AC, Kussendrager KD, Steijns JM., In vivo antimicrobial and antiviral activity of components in bovine milk and colostrum involved in non-specific defence., Br J Nutr. 2000 Nov;84 Suppl 1:S127-34. Related Articles, Links,DMV International, R&D Center, PO Box 13, 5460 BA Veghel, The Netherlands.
Shortridge, KF, Lawton, JW, Choi, EK. Protective potential of colostrum and early milk against prospective influenza viruses. Journal of Tropical Pediatrics 36(2):94-95 (1990).
Rump JA, Arndt R, Arnold A, Bendick C, Dichtelmuller H, Franke M, Helm EB, Jager H, Kampmann B, Kolb P, et al. Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clin Investig. 1992 Jul;70(7):588-94.
Pizza, G, Amadori, M, Ablashi, D, De Vinci, C, Viza, D. (2006). Cell mediated immunity to meet the avian influenza A (H5N1) challenge. Medical Hypoteses 67(3):601-8. As no vaccine can be made ahead of time for a possible bird flu pandemic, cell mediated immunity via specific transfer factor (PRP) may be useful for both the prevention and treatment of infection.
Petschow, BW, Talbott, RD. Reduction in virus-neutralizing activity of a bovine colostrum immunoglobulin concentrate by gastric acid and digestive enzymes. Journal of Pediatric Gastroenterology and Nutrition 19(2):228-235 (1994).
Palmer,E.L. et al. Antiviral Activity of Colostrum and Serum Immunoglobulins A and G. J. Med. Virol. 5:123-129. 1980.
Mitra AK, Mahalanabis D, Ashraf H, Unicomb L, Eeckels R, Tzipori S. Acta Paediatr. 1995 Sep;84(9):996-1001. Related Articles, Links, Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), Dhaka Bangladesh.
Immunoglobulin components and anti-viral activities in bovine colostrum. Kansenshogaku Zasshi. 1990 Mar;64(3):274-9.